ImmunologybioRxivPreprint
An ITK - SLP-76 Y173 Axis Regulates TCR Signal Persistence and Thymic Development
Manal Marzouk, J Perry, Enas Hallumi…·Deborah Yablonski
This study shows that the ITK-SLP-76 Y173 axis is essential for TCR signal persistence and thymic development, as its disruption reduces thymocyte cellularity and alters CD4/CD8 ratios.
DOI 10.64898/2026.10.22.760889