Author

Leslie J. Berg

University of Colorado AnschutzORCID 0000-0001-6031-7542Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Alayna Rosales· 2 shared Abhyudai SinghiD· 1 shared Brendan MonogueiD· 1 shared Camille Merrick· 1 shared Deborah YablonskiiD· 1 shared Dominic P. GoleciD· 1 shared Dustin L. Heiden· 1 shared Enas HallumiiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersImmunology

Alayna Rosales

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintOct 27, 2026

An ITK - SLP-76 Y173 Axis Regulates TCR Signal Persistence and Thymic Development

Manal Marzouk, J Perry, Enas Hallumi…·Deborah Yablonski

This study shows that the ITK-SLP-76 Y173 axis is essential for TCR signal persistence and thymic development, as its disruption reduces thymocyte cellularity and alters CD4/CD8 ratios.

DOI 10.64898/2026.10.22.760889

mouseexperimental assay

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ImmunologyThe Journal of ImmunologyPeer-reviewedMay 1, 2026

Myeloid cell IL-15 production in the brain supports Bystander CD8+ T-Cell Neuropathic Immune Responses following Virus infection

Jennifer N. Berger, Alayna Rosales, Dustin L. Heiden…·Leslie J. Berg

1 citation

mouseproteomics

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ImmunologybioRxivPreprintSep 22, 2025

Regulation of TCR-induced Transcriptional Kinetics by Interleukin 2-inducible T Cell Kinase (ITK) in CD8+ T cells

Josh Hunkins, Zoe K. Bedrosian, Uddeep Chaudhury…·Leslie J. Berg

This study shows ITK differentially regulates early and late TCR transcriptional responses by affecting the kinetics and termination of activation signals in CD8+ T cells.

DOI 10.1101/2025.09.22.677398

mouseflow cytometry

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