Author

Hai L. Tran

Denali Therapeutics (United States)ORCID 0000-0003-3715-8111Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1 Organism:non-human primate· 1

Frequent Co-Authors

Akhila Palakodaty· 1 shared Alberto Ponce· 1 shared Alexander J. MartinkoiD· 1 shared Alexander StergioulisiD· 1 shared Alfred E. ChappelliD· 1 shared Allisa J. Clemens· 1 shared Allison L. CookeiD· 1 shared Anthony A. EstradaiD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperSynthetic Biology

Akhila Palakodaty

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintApr 25, 2023

Targeting Transferrin Receptor to Transport Antisense Oligonucleotides Across the Blood-Brain Barrier

Scarlett J. Barker, Mai B. Thayer, Chaeyoung Kim…·Sarah L. DeVos

This paper demonstrates that systemically delivered OTV, a TfR-binding molecule, effectively transports ASO across the BBB, achieving widespread and sustained knockdown of target genes in the CNS of mice and non-human primates.

21 citations

mousenon-human primate

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Synthetic BiologybioRxivPreprintApr 11, 2023

A bioorthogonal antibody-based chemically-induced-dimerization switch for therapeutic application

Alexander J. Martinko, Hai L. Tran, Erin F. Simonds…·Zachary B. Hill

The paper introduces a CID system using humanized antibodies and a clinically approved drug for controlled therapeutic applications.

1 citation

humanexperimental assay

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