Author

Richard D. Schargel

Cornell UniversityORCID 0000-0003-3741-009XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:gene regulatory network inference· 2 Organism:bacteria (other)· 1 Assay:CRISPR screen· 1 Research Focus:protein design· 1

Frequent Co-Authors

Joseph E. PetersiD· 3 shared Jordan E. ThesieriD· 2 shared Shan-Chi HsiehiD· 2 shared Alba GuarnéiD· 1 shared Laura Chacon MachadoiD· 1 shared Máté FülöpiD· 1 shared Michael T. PetassiiD· 1 shared O. BarábasiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersMicrobiology

Joseph E. PetersORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintAug 27, 2025

De novo engineered guide RNA-directed transposition with TnpB-family proteins reveals features of naturally evolved systems

Richard D. Schargel, Laura Chacon Machado, Shravanika Kumaran…·Joseph E. Peters

This paper engineers de novo RNA-guided transposition systems using TnpB-family proteins, showing improved specificity and efficiency compared to naturally evolved systems.

2 citations

CRISPR screenexperimental assay

𝕏 PostBluesky

MicrobiologybioRxivPreprintJul 27, 2025

Tn7 family bacterial transposons known for tightly controlled target site selection are distributed across Asgard and archaeal groups

Jordan E. Thesier, Shan-Chi Hsieh, Richard D. Schargel…·Joseph E. Peters

The paper identifies diverse Tn7 family transposons in archaea, including Asgard groups, and shows they target specific sites like tRNA and ribonucleotide reductase genes.

DOI 10.1101/2025.07.27.667033

experimental assaychromatin & epigenetic regulation

𝕏 PostBluesky

MicrobiologySciencePeer-reviewedMar 6, 2025

Telomeric transposons are pervasive in linear bacterial genomes

Shan-Chi Hsieh, Máté Fülöp, Richard D. Schargel…·Joseph E. Peters

The paper identifies telomeric transposons in cyanobacteria and Streptomyces that replace native telomeres and influence genome evolution.

8 citations

bacteria (other)experimental assay

𝕏 PostBluesky