NeurosciencebioRxivPreprint
A dual hit of α-synuclein internalization and immune challenge leads to formation and maintenance of Lewy body-like inclusions in human dopaminergic neurons
Armin Bayati, Riham Ayoubi, Adriana Aguila…·Peter Scottt McPherson
The paper shows that combining α-synuclein fibrils with immune challenges causes Lewy body-like inclusions in human dopaminergic neurons, while cortical neurons do not form such inclusions.
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