Author

Armin Bayati

Harvard UniversityORCID 0000-0002-5960-0479Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Thomas M. DurcaniD· 3 shared Jackson G. SchumacheriD· 2 shared Jo Anne StrattoniD· 2 shared Moein YaqubiiD· 2 shared Peter Scottt McPhersoniD· 2 shared Wen LuoiD· 2 shared Xiqun CheniD· 2 shared Adam MacDonaldiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersNeuroscience

Thomas M. DurcanORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Neural cell state modulation by PARK2 and dopaminergic neuroprotection by small molecule Parkin agonism

Yongxing Gong, Armin Bayati, Tyler Joseph Alban, Prerana Bangalore Parthasarathy, Fang Zhou, Vladimir Makarov, Yuhang Zhao, Chien‐Wen Su, Jackson G. Schumacher, Vijay Singh, Laura A. Volpicelli‐Daley, Wen Luo, Thomas M. Durcan, Shovan Dutta, Michael A. Schwarzschild, , Xiqun Chen

This study shows that Parkin is essential for neuronal differentiation and survival, and small molecule Parkin agonists like FB231 protect dopaminergic neurons in Parkinson's disease models.

bioRxiv · Apr 4, 2026 · PreprintNeuroscience

Myeloid PINK1 represses mtDNA release and immune signaling that impacts neuronal pathology in patient-derived idiopathic PD models

Sherilyn Junelle Recinto, Adam MacDonald, Shobina Premachandran, Lin Liu, Armin Bayati, Lilia Rodriguez, Mai Nguyen, Florence Petit, Sriparna Mukherjee, Julien Larmanjat, Alexis Allot, Moein Yaqubi, Peter Scottt McPherson, Thomas M. Durcan, Samantha Gruenheid, , Jo Anne Stratton

This study shows that PINK1 in myeloid cells represses mtDNA release and immune signaling, which contributes to neuronal pathology in Parkinson's disease models.

bioRxiv · Jan 8, 2026 · PreprintImmunology

AutoMorphoTrack: A modular framework for quantitative analysis of organelle morphology, motility, and interactions at single-cell resolution

Armin Bayati, Jackson G. Schumacher, Xiqun Chen

AutoMorphoTrack automates organelle morphology, motility, and interaction analysis from fluorescence microscopy images, providing reproducible, publication-ready outputs.

bioRxiv · Jul 19, 2025 · PreprintNeuroscience

A dual hit of α-synuclein internalization and immune challenge leads to formation and maintenance of Lewy body-like inclusions in human dopaminergic neurons

Armin Bayati, Riham Ayoubi, Adriana Aguila, Cornelia E. Zorca, Chanshuai Han, Emily Banks, Emmanuelle Nguyen, Wen Luo, Irina Shlaifer, Esther del Cid‐Pellitero, Moein Yaqubi, Edward A. Fon, Jo Anne Stratton, Thomas M. Durcan, Patrick C. Nahirney, Peter Scottt McPherson

The paper shows that combining α-synuclein fibrils with immune challenges causes Lewy body-like inclusions in human dopaminergic neurons, while cortical neurons do not form such inclusions.

bioRxiv · May 29, 2023 · PreprintNeuroscience