Drug Proarrhythmic Evaluation in a High Throughput Cardiac New Approach Methodology
Verena Charwat, Adrian Ramirez, Karoline Horgmo Jæger…·Samuel Wall
This paper develops a high-throughput cardiac NAM using hiPSC-derived cardiomyocytes to evaluate drug proarrhythmic potential, showing accurate detection of arrhythmic risk and insights into ion channel effects.