Manoj Kumar

This study investigates how all-trans retinoic acid (ATRA) affects macrophage gene expression in response to different drug-resistant Mycobacterium tuberculosis strains, revealing strain-specific transcriptional changes and potential therapeutic targets.

TOXsiRNA predicts the toxicity of chemically modified siRNAs using machine learning models trained on sequence features.

PEPsRNA is a database of experimentally tested peptide-based siRNA delivery systems, providing 2266 entries with analysis of peptides, siRNAs, and conjugates.

The paper identifies repurposing drugs targeting host genes for HCV infection and related HCC by analyzing transcriptomic data from human liver tissues.

This study shows that defects in mitochondrial biogenesis, not mitophagy, are the primary cause of mitochondrial alterations in PINK1-deficient human dopamine neurons.

The paper analyzes metagenomic data from river Ganges sediments to identify phages, microbial taxa, and antibiotic resistance genes, revealing their abundance and diversity.

This study compares microarray and RNA-seq expression profiling of Nipah virus to identify differentially expressed genes and potential drug targets.

The paper establishes the landscape of human cell-specific microRNA expression using small RNA-seq data from diverse cell types and tissues, identifying novel microRNA loci and patterns correlated with super-enhancer activity.