Author

Showkat Ahmad Dar

Institute of Microbial TechnologyORCID 0000-0002-5077-1925Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Genomics· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Cédric BelairiD· 2 shared Manoj KumariD· 2 shared Manolis MaragkakisiD· 2 shared Na YangiD· 2 shared Payel SeniD· 2 shared Abid RehmaniD· 1 shared Carlos AnerillasiD· 1 shared Chang‐Yi CuiiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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2 shared papersGenomics

Cédric BelairORCID

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4 papers

Recent·Most cited

TOXsiRNA: A web server to predict the toxicity of chemically modified siRNAs

Showkat Ahmad Dar, Manoj Kumar

TOXsiRNA predicts the toxicity of chemically modified siRNAs using machine learning models trained on sequence features.

bioRxiv · Feb 14, 2026 · PreprintBioinformatics

PEPsRNA: A computational resource of experimentally tested peptide based siRNA delivery

Showkat Ahmad Dar, Manoj Kumar

PEPsRNA is a database of experimentally tested peptide-based siRNA delivery systems, providing 2266 entries with analysis of peptides, siRNAs, and conjugates.

bioRxiv · Feb 13, 2026 · PreprintBioinformatics

Cell-specific RNA isoform remodeling in the aging mouse brain

Abid Rehman, Megan F. Duffy, Katarína Grešová, Cédric Belair, Na Yang, Lin Wang, Christopher Tai-Yi Lee, Matthew John Payea, Sulochan Malla, Showkat Ahmad Dar, Payel Sen, Mark Cookson, Manolis Maragkakis

This study identifies cell-type-specific RNA isoform changes in aging mouse brain using single-cell and long-read sequencing, revealing altered coding potential and senescence markers in immune cells.

bioRxiv · Jun 5, 2025 · PreprintGenomics

Gene body DNA hydroxymethylation restricts the magnitude of transcriptional changes during aging

James R. Occean, Na Yang, Yan Sun, Marshall S. Dawkins, Rachel B. Munk, Cédric Belair, Showkat Ahmad Dar, Carlos Anerillas, Lin Wang, Changyou Shi, Christopher Dunn, Michel Bernier, Nathan L. Price, Julie S. Kim, Chang‐Yi Cui, , Payel Sen

This study shows that DNA hydroxymethylation in gene bodies limits transcriptional changes with age in mouse and human tissues.

Nature Communications · Jul 28, 2024Peer-reviewedGenomics