Author

Geoffrey A. M. Neale

St. Jude Children's Research HospitalORCID 0000-0003-3776-0858Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:DNA methylation· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

Emily V. WalkeriD· 2 shared Zhaoming WangiD· 2 shared Aditya ShethiD· 1 shared Amber L. SmithiD· 1 shared Amy SchneideriD· 1 shared Bekim SadikovićiD· 1 shared Carmen Louise WilsoniD· 1 shared Cassandra RastiniD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Emily V. WalkerORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologyScience AdvancesPeer-reviewedJan 1, 2025

Somatic mtDNA Mutation Burden Shapes Metabolic Plasticity in Leukemogenesis

Xiujie Li-Harms, Jingjun Lü, Yu Fukuda…·Mondira Kundu

This study shows that somatic mtDNA mutations affect metabolic plasticity in leukemia development, with heterozygous mutations supporting NMyc-driven leukemia while homozygous mutations impair it.

9 citationstop 3%

mousemetabolomics

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Genetic & Genomic MedicineNature CommunicationsPeer-reviewedAug 6, 2024

Diagnostic Utility of Genome-wide DNA Methylation Analysis in Genetically Unsolved Developmental and Epileptic Encephalopathies and Refinement of a CHD2 Episignature

Christy W. LaFlamme, Cassandra Rastin, Soham Sengupta…·Heather C. Mefford

This study evaluates genome-wide DNA methylation analysis in genetically unsolved DEEs, identifying 10 causative or candidate genetic causes and refining a CHD2 episignature.

31 citationstop 1%

humanDNA methylation

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Genetic & Genomic MedicineGenome MedicinePeer-reviewedApr 6, 2021

Persistent Variations of Blood DNA Methylation Associated with Treatment Exposures and Risk for Cardiometabolic Outcomes among Long-term Survivors of Childhood Cancer: A Report from the St. Jude Lifetime Cohort

Nan Song, Chia‐Wei Hsu, Haitao Pan…·Zhaoming Wang

This study identifies DNA methylation sites associated with cancer treatments and mediates cardiometabolic risks in childhood cancer survivors.

35 citationstop 3%

humanDNA methylation

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