Ryan A. Senne

This paper introduces a drift diffusion model with hidden Markov states to analyze time-dependent decision-making in rats, revealing daily fluctuations in performance linked to circadian rhythms.

The paper introduces a state-dependent drift diffusion model to show mice switch between impulsive and deliberative decision states during tasks, revealing active exploration of the speed-accuracy trade-off.

This study identifies astrocytic calcium-event sequences in the dorsal hippocampus during learning and memory tasks, showing they encode time-compressed information similar to neuronal time cells.

This paper develops a cross-species evidence accumulation task to compare perceptual decision-making in humans, rats, and mice, finding similar strategies but species-specific priorities in speed, accuracy, and reward optimization.

This study tracks CA1 engram cell dynamics before and after learning, showing they are influenced by intrinsic activity, behavior, and memory.

This study shows that optogenetic reactivation of fear memories in the hippocampus reproduces cellular activity patterns seen during natural memory recall, highlighting neuronal-astrocytic coupling in fear behavior.

This study shows that basolateral amygdala astrocytes are responsive to fear memory acquisition and recall, with distinct calcium dynamics during fear conditioning and extinction.

The paper reactivates hippocampal fear engrams across different contexts and identifies brain-wide network changes associated with distinct defensive behaviors.

This study investigates how ethanol exposure affects fear memory processing in mice and shows that optogenetic inhibition of hippocampal engrams reduces maladaptive contextual generalization.