Evan A. Ruesch

The paper shows that hippocampal place field remapping and coordinated ensemble activity, dependent on protein synthesis, are critical for contextual fear memory consolidation.

This study identifies astrocytic calcium-event sequences in the dorsal hippocampus during learning and memory tasks, showing they encode time-compressed information similar to neuronal time cells.

This study shows that repeated activation of negative memory engrams in mice leads to lasting cellular and behavioral abnormalities, similar to chronic negative thinking in humans.

The paper reactivates hippocampal fear engrams across different contexts and identifies brain-wide network changes associated with distinct defensive behaviors.

The paper shows that reactivating positive memories during fear memory recall reduces conditioned fear in mice, suggesting a method to disrupt negative affective states through memory updating.

This study investigates how ethanol exposure affects fear memory processing in mice and shows that optogenetic inhibition of hippocampal engrams reduces maladaptive contextual generalization.

The paper identifies distinct cell populations in the ventral hippocampus that encode appetitive and aversive memories, showing molecular, cellular, and projection-specific differences.

The paper investigates trajectory-dependent splitter neurons in mice, finding they are more stable than place cells and support memory-guided navigation.