Author

Alejandra Montaño Romero

Johns Hopkins UniversityORCID 0000-0003-3779-2147Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:cryo-EM· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Edward C. TwomeyiD· 2 shared Albert Y. LauiD· 1 shared Andreea L. TurcuiD· 1 shared Cuauhtemoc Ulises GonzaleziD· 1 shared Elisa Cristina CarrilloiD· 1 shared Hong Chen· 1 shared Hui‐Lin PaniD· 1 shared Remy A. YovannoiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiophysics

Edward C. TwomeyORCID

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2 papers

Recent·Most cited

Memantine Inhibits Calcium-Permeable AMPA Receptors

Elisa Cristina Carrillo, Alejandra Montaño Romero, Cuauhtemoc Ulises Gonzalez, Andreea L. Turcu, Shao-Rui Chen, Hong Chen, Hui‐Lin Pan, Santiago Vázquez, Edward C. Twomey, Vasanthi Jayaraman

This study shows memantine inhibits calcium-permeable AMPA receptors, revealing a new mechanism distinct from NMDA receptors and suggesting therapeutic potential for neurological disorders.

Nature Communications · Jul 1, 2025Peer-reviewedBiophysics

Mechanisms of Ion Permeation in the AMPA Receptor Ion Channel

Alejandra Montaño Romero, Remy A. Yovanno, Albert Y. Lau, Edward C. Twomey

This study identifies ion permeation pathways in AMPARs using cryo-EM and MD simulations, showing how mutations affect ion flow and susceptibility to blockage.

bioRxiv · Jun 27, 2025 · PreprintBiophysics