Sven Hildebrand

This study uses two-photon microscopy with MASH clearing to image 3D structures of invasive ductal carcinoma breast tissue and axillary lymph nodes, revealing ECM remodeling in early-stage tumors.

This paper introduces angioMASH, a method to visualize vascular and cytoarchitectonic features in human brain tissue, revealing layer-specific vascular density and orientation differences in visual areas V1 and V2.

The paper introduces an improved open-source light-sheet microscope, mesoSPIM, with enhanced resolution, throughput, and compatibility with cleared samples.

The paper introduces a novel Schmidt objective for high-resolution imaging in cleared tissues, achieving high NA, long WD, and large FOV with only two optical elements.

This paper demonstrates a light-sheet microscopy technique for 3D imaging of large human tissue samples with high resolution and speed, showing potential for clinical applications in prostate cancer.

The paper introduces MASH, a method for cytoarchitectonic labeling and optical clearing of human cortex samples, enabling scalable 3D characterization of neocortical cytoarchitecture.

The paper introduces mesoSPIM, an open-source light-sheet microscope initiative for imaging large cleared tissue samples with near-isotropic resolution.