Author

Jade Tassey

University of Southern CaliforniaORCID 0000-0003-3808-4214Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Denis A. EvseenkoiD· 3 shared Andrew C. Drake· 2 shared Arijita SarkariD· 2 shared Fangzhou Bian· 2 shared Hanhan Tang· 2 shared Jenny MagallanesiD· 2 shared Jichen Yang· 2 shared Jinxiu Lu· 2 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCell Biology

Denis A. EvseenkoORCID

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintFeb 9, 2026

GP130 Y814 SIGNALING IS REQUIRED FOR THE DYNAMIN-MEDIATED ENDOCYTOSIS, MAPK/P38 ACTIVATION AND PERSISTENCE OF CHRONIC SYSTEMIC INFLAMMATION INDUCED BY HIGH FAT DIET

Jade Tassey, Y.-J. Lee, Jichen Yang…·Denis A. Evseenko

This study shows that gp130-Y814 signaling is critical for dynamin-mediated endocytosis, MAPK/p38 activation, and chronic inflammation persistence in high-fat diet models.

DOI 10.64898/2026.02.06.704505

mouseproteomics

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Cell BiologyScientific ReportsPeer-reviewedDec 28, 2024

Inactivation of a non-canonical gp130 signaling arm attenuates chronic systemic inflammation and multimorbidity induced by a high-fat diet.

Y.-J. Lee, Jade Tassey, Arijita Sarkar…·Denis A. Evseenko

This study shows that inhibiting a non-canonical gp130 signaling pathway reduces chronic inflammation and multimorbidity in a high-fat diet model.

5 citations

mouseexperimental assay

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Molecular BiologyAging CellPeer-reviewedJan 13, 2023

Genome-wide DNA methylation and multi-omics study of human chondrocyte ontogeny and an epigenetic clock analysis of adult chondrocytes

Arijita Sarkar, Nancy Q. Liu, Jenny Magallanes…·Denis A. Evseenko

This study examines DNA methylation changes in human chondrocytes across ontogeny and develops an epigenetic clock showing STAT3 agonist reduces epigenetic age in aged chondrocytes.

42 citationstop 1%

humanDNA methylation

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