Vincent Mouly

This study identifies age-related changes in the muscle secretome that impair stem cell function through sphingolipid metabolism alterations.

This study examines the effects of AGEs on a human neuromuscular junction co-culture model, revealing structural, metabolic, and functional impairments.

This study investigates Oropouche virus infection in human cell types and its ability to cross the blood-brain barrier, finding broad tropism and neuronal vulnerability.

The paper shows mini-agrin prevents calcium leakage and restores the dystrophin complex in dystrophic muscle cells by stabilizing CaV1.1 and reconstituting dystrophin complex components.

This study identifies collagen VI as a conserved pro-fibrotic factor that impairs muscle regeneration in three distinct human myopathies.

This study shows that PRDX2 mediates redox-stimulated adaptations to oxidative phosphorylation in human skeletal muscle myotubes exposed to contractile activity or H2O2.

This study compares the effects of endurance and resistance exercise on OPMD skeletal muscle in mice, finding that resistance exercise reduces PABPN1 aggregates and reverses muscle atrophy, while endurance exercise increases aggregates and collagen deposition.

This study shows SMCHD1 loss causes DUX4 expression in FSHD2 by disrupting splicing of DNMT3B, leading to hypomethylation and muscle abnormalities.

This study shows that guanabenz acetate reduces PABPN1 aggregates and improves muscle function in an OPMD mouse model by modulating the UPR.

This study shows that clathrin plaques and dynamin 2 anchor desmin intermediate filaments and regulate YAP signaling in skeletal muscle in response to mechanical cues.