Malcolm Joseph Jackson

This study examines proteomic changes in human muscle constructs under microgravity and shows that HSP10 overexpression reduces these changes, suggesting a potential strategy for combating muscle atrophy.

The paper describes the design and operational considerations of a tissue-engineered skeletal muscle system for microgravity experiments to study muscle atrophy and aging mechanisms.

This study shows that PRDX2 mediates redox-stimulated adaptations to oxidative phosphorylation in human skeletal muscle myotubes exposed to contractile activity or H2O2.