Cell BiologybioRxivPreprint
KIF1A-driven entry of degradative lysosomes into the axon is developmentally regulated by the microtubule environment at the axon initial segment
Nireekshit Addanki Tirumala, Surbhi Verma, Juan S. Bonifacino
This study shows that KIF1A-mediated lysosomal transport into axons is regulated by the axon initial segment microtubule environment, and its disruption leads to axonal degeneration.