Lázaro Centanin

The paper creates a spatial transcriptomics map of the embryonic mouse brain to explore neurogenesis by integrating single-cell RNAseq data and identifying cell type-specific transcriptional signatures.

The paper identifies organ-founder stem cells that mediate post-embryonic neuromast formation in medaka fish, showing their dynamic behavior and role in organogenesis.

The paper develops a mathematical model to estimate stem cell numbers and identify functional heterogeneities in fish gill growth using a Markov model and stochastic simulations.

The paper identifies a conserved enhancer in the FLT1 locus that drives cardiovascular expression and modulates angiogenesis pathways in vitro and in vivo.

The paper shows that epithelial integrity guides neuromast positioning in medaka's posterior lateral line, independent of neuronal wiring.

The paper uses inter-species blastula transplants in zebrafish and medaka to show that developmental modules like the retina follow autonomous genetic programs, decoupling from host timing.

This study identifies desmogon as essential for vacuolated cell shape and notochord morphology in Medaka, revealing developmental heterogeneity and injury sensing mechanisms.

The paper identifies distinct homeostatic and growth adult stem cell populations in medaka gills, showing their spatial separation and functional specialization.

The paper shows retinal stem cells in fish coordinate post-embryonic eye growth by modulating cell division parameters between neural retina and retinal pigmented epithelium.

The paper shows neural stem cells induce the formation of an outer border cell lineage during medaka organogenesis through clonal analysis and 4D imaging.