Author

Esther C. H. Uijttewaal

Institute of Molecular BiotechnologyORCID 0000-0003-3892-2820Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Alan HuangiD· 1 shared Alborz BejnoodiD· 1 shared Ali OghabianiD· 1 shared Annabel Devault· 1 shared Ashley H Choi· 1 shared Bas de WolfiD· 1 shared ‎Berend SneliD· 1 shared Bertrand IsidoriD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

Alan HuangORCID

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2 papers

Recent·Most cited

GenomicsCell Reports MethodsPeer-reviewedJun 1, 2026

Temporal control of sgRNA library activation unlocks large-scale in vivo CRISPR screens

Silvia Fenoglio, Yi Yu, James Tepper…·Teng Teng

This paper introduces CRISPR-StAR, an in vivo CRISPR screening platform with improved normalization and analysis tools, showing it can identify tumor suppressor gene effects not observable in vitro.

1 citation

humanCRISPR screen

𝕏 PostBluesky

Molecular BiologybioRxivPreprintAug 6, 2020

Chromosomal instability by mutations in a novel specificity factor of the minor spliceosome

Bas de Wolf, Ali Oghabian, Maureen V. Akinyi…·Geert J.P.L. Kops

The paper identifies biallelic mutations in CENATAC as a cause of constitutional aneuploidy by disrupting minor intron splicing and causing chromosome segregation errors.

1 citation

humanwhole-exome sequencing

𝕏 PostBluesky