Janaína Sena de Souza

This study shows that SETD5 dysfunction in astrocytes increases IL-6, which harms neurons via JAK/STAT signaling, suggesting therapeutic targeting of this pathway for ASD and ID.

The paper identifies non-CGG trinucleotide repeat mutations in the FMR1 gene associated with Fragile X Syndrome phenotypes, suggesting broader genetic screening is needed beyond CGG repeats.

This study shows therapeutic acetaminophen exposure does not significantly alter human cortical organoid development at the molecular or functional level.

The paper introduces AmpliDrop, a single-cell genomics barcoding technology that simplifies reagent production and workflow, enabling scalable and flexible experiments.