Ivan García-Bassets

SETD5 dysfunction in human astrocytes drives IL-6-mediated neuronal impairments via the JAK/STAT signaling pathway

This study shows that SETD5 dysfunction in astrocytes increases IL-6, which harms neurons via JAK/STAT signaling, suggesting therapeutic targeting of this pathway for ASD and ID.

Aberrant gliogenesis and excitation in MEF2C autism patient hiPSC-neurons and cerebral organoids

Autism-like MEF2C+/- patient hiPSC models show miRNA-mediated overproduction of astrocytes and hyperactivity of neurons.

Single-Molecule Barcoding Technology for Single-Cell Genomics

The paper introduces AmpliDrop, a single-cell genomics barcoding technology that simplifies reagent production and workflow, enabling scalable and flexible experiments.

Targeted Phasing of 2-200 Kilobase DNA Fragments with a Short-Read Sequencer and a Single-Tube Linked-Read Library Method

This paper introduces an optimized TELL-Seq protocol for cost-effective phasing of targeted genomic loci using short-read sequencing.