Kazuhiro Maeshima

The paper uses machine learning to classify chromatin classes and shows how different transcription systems affect nucleosome motion in distinct chromatin regions.

The paper measures local nucleosome motion in living human cells during interphase and finds it remains nearly constant, with changes observed under specific perturbations.

This study shows cohesin maintains condensed euchromatic domains in human cells by preventing local mixing, which is crucial for transcriptional insulation.

This study shows that linker histone H1 acts as a liquid-like glue in chromatin domains, enabling dynamic interactions that support DNA transactions in human cells.

The paper investigates how BRD4-NUT condensates physically constrain chromatin movement in human cells through liquid-like dynamics and nucleosome crosslinking.

The paper develops Repli-Histo labeling to study nucleosome motion in euchromatin and heterochromatin, finding that euchromatic regions exhibit greater motion and influence replication timing.

This study uses electron cryotomography to show that budding yeast chromatin lacks 30-nm fibers and is in an open configuration, suggesting transcription regulation through local nucleosome interactions.