This paper develops a commensal Engineered Living Material (cELM) that encapsulates bacteria to deliver a pro-healing secretome for chronic wound healing.

DOI 10.64898/2026.11.04.764344

mouseexperimental assay

𝕏 PostBluesky

Cell BiologyToxicological SciencesPeer-reviewedOct 24, 2026

Single-cell analysis of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-treated murine skin demonstrates that sebaceous gland differentiation precedes Ahr-dependent seboatrophy with elevated expression of infundibular Blimp1

Syeda Mashnia Tasnim, Subhash Solanki, Jyoti Bhuju…·Thomas R. Sutter

This study shows TCDD induces Cyp1a1 in murine skin, enhancing sebaceous gland differentiation and lipid production before causing Ahr-dependent seboatrophy.

DOI 10.1093/toxsci/kfag141

mousescRNA-seq

𝕏 PostBluesky

Cell BiologybioRxivPreprintJun 16, 2026

Microbiota-derived butyrate promotes dermal collagen production through epidermal-dermal crosstalk

Jamie Ting-Chun Pan, Sofía M. Murga-Garrido, Deborah Minzaghi…·Elizabeth A. Grice

This study shows that microbiota-derived butyrate enhances dermal collagen production via epidermal-dermal signaling, revealing a novel microbiota-epidermis-dermis axis.

DOI 10.64898/2026.06.15.731906

humanmouse

𝕏 PostBluesky

GenomicsbioRxivPreprintSep 27, 2018

The microbial basis of impaired wound healing: differential roles for pathogens, \"bystanders\", and strain-level diversification in clinical outcomes

Lindsay Kalan, Jacquelyn S. Meisel, Michael A. Loesche…·Elizabeth A. Grice

This study investigates the role of microbial communities in diabetic foot ulcer healing, finding that strain-level diversity of Staphylococcus aureus and other microbes influence clinical outcomes.

7 citations

humanmetagenomics

𝕏 PostBluesky