Lindsay Kalan

The paper compares immune profiles and microbiomes of breast milk from mothers with different farm exposures to identify associations with immune development and atopic disease.

The paper investigates antimicrobial activity in the skin microbiome, identifies novel defensive species, and highlights dry skin sites as rich sources of bioactive metabolites.

The paper isolates Streptomyces from cadaveric fly larvae, identifies bioactive compounds, and demonstrates their anthelmintic activity against Brugia malayi.

This paper establishes an ex vivo porcine skin model to study antiseptic effects on microbial communities and lipids, finding chlorhexidine gluconate reduces culturable microbes but increases Gram-negative taxa.

The paper links multicellularity with expanded chemical arsenals in microbes by showing that multicellular lineages have greater biosynthetic potential for specialized metabolites.

The paper introduces two tools, skDER and CiDDER, for microbial genome dereplication to select representative genomes for comparative genomic studies.

This study shows that chlorhexidine gluconate reduces viable skin microbial bioburden but does not achieve complete sterility, and temporarily increases pathogen abundance before microbiome recovery.

The paper introduces fai and zol for large-scale comparative analysis of gene clusters and MGEs, enabling comprehensive orthology inference and evolutionary studies across thousands of genomes.

This study shows that Corynebacterium amycolatum produces cobamides and shares them with E. coli, supporting its growth through cobamide synthesis and spatial separation.

This study compares nasal and oral microbiomes of infants and adults, finding age-related differences in diversity, composition, and functional capabilities.

The paper examines oral microbiota differences between individuals carrying multidrug-resistant gram-negative bacilli and non-carriers, finding reduced inhibition of pathogens and altered resistome profiles.

This study characterizes the porcine skin microbiome, identifies antifungal bacterial isolates, and discovers novel fungal and bacterial species with potential for antifungal applications.

This study shows that Malassezia sympodialis reduces Staphylococcus aureus colonization on human skin and identifies Rel variants that confer antibiotic tolerance in response to fungal antagonism.

The paper introduces lsaBGC, a bioinformatics tool for analyzing BGCs in skin microbiomes, revealing evolutionary patterns and novel SNVs in key species.

vRhyme is a software tool that bins viral genomes from metagenomes, producing more complete and uncontaminated viral metagenome-assembled genomes (vMAGs) than existing methods.

This study investigates the role of microbial communities in diabetic foot ulcer healing, finding that strain-level diversity of Staphylococcus aureus and other microbes influence clinical outcomes.