Author

Juan Luengo-Márquez

Universidad Complutense de MadridORCID 0000-0003-3945-6665Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 3 Approach:statistical model· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Assay:long-read sequencing· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Alberto OcanaiD· 3 shared Andrés R. TejedoriD· 3 shared Jorge R. EspinosaiD· 3 shared Rosana Collepardo‐GuevaraiD· 3 shared Pablo Llombart GonzáleziD· 2 shared Alejandro CastroiD· 1 shared Álvaro OteroiD· 1 shared Eduardo PedrazaiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersBiophysics

Alberto OcanaORCID

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3 papers

Recent·Most cited

BiophysicsbioRxivPreprintSep 17, 2026

Size Control of hnRNPK-based Nucleolar Condensates by RNA-Regulated Fusion Dynamics

Andrés R. Tejedor, Juan Luengo-Márquez, Pablo Burriel Llombart…·Jorge R. Espinosa

This study identifies how RNA-regulated fusion dynamics of hnRNPK-based nucleolar condensates prevent coalescence and maintain size control.

DOI 10.64898/2026.09.14.751346

deep learningstatistical model

𝕏 PostBluesky

BiophysicsbioRxivPreprintJun 12, 2026

The physical origin of ageing at biomolecular condensate interfaces

Alejandro Castro, Juan Luengo-Márquez, Andrés R. Tejedor…·Jorge R. Espinosa

This study shows that cross-β-sheet nucleation, linked to ageing, preferentially occurs at biomolecular condensate interfaces due to a general physical mechanism, not specific protein sequences.

2 citations

deep learningstatistical model

𝕏 PostBluesky

BiophysicsbioRxivPreprintApr 26, 2026

RNA2PS: A sequence-specific coarse-grained RNA model linking structure, thermodynamics and phase separation

Andrés R. Tejedor, Juan Luengo-Márquez, J. Oller-Iscar…·Jorge R. Espinosa

RNA2PS predicts RNA structure and phase separation behavior from sequence, showing sequence-dependent duplex stability and condensation differences in trinucleotide repeat RNAs.

1 citation

long-read sequencingstructural biology

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