Author

Karīna Siliņa

ETH ZurichORCID 0000-0003-3947-2710Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetic & Genomic Medicine· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1

Frequent Co-Authors

Agshin Balayev· 1 shared Ala’a Al HroutiD· 1 shared Anna Laura CalvaneseiD· 1 shared Burkhard LudewigiD· 1 shared Christoph SchneideriD· 1 shared Daniel SchnepfiD· 1 shared Gunnar RätschiD· 1 shared Holger MochiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCancer Biology

Agshin Balayev

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologyScience AdvancesPeer-reviewedOct 8, 2025

Melanoma Response to Immunotherapy is regulated by B Cell-Derived Extracellular Vesicles

Ala’a Al Hrout, Agshin Balayev, Karla Cervantes-Gracia…·Richard Chahwan

This study identifies B cell-derived extracellular vesicles and miR-99a-5p as key regulators of melanoma response to immunotherapy.

7 citations

humanbulk RNA-seq

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Genetic & Genomic MedicinemedRxivPreprintFeb 9, 2025

DeepSpot: Leveraging Spatial Context for Enhanced Spatial Transcriptomics Prediction from H&E Images

Kalin Nonchev, Sebastian Dawo, Karīna Siliņa…·Gunnar Rätsch

DeepSpot predicts spatial transcriptomics from H&E images, improving gene correlations across cancer datasets and generating virtual spatial transcriptomics samples.

15 citations

humanspatial transcriptomics

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ImmunologyEuropean Journal of ImmunologyPeer-reviewedJul 9, 2024

Sustained innate interferon is an essential inducer of tertiary lymphoid structures

Anna Laura Calvanese, Virginia Cecconi, Severin Stäheli…·Maries F. van den Broek

This study identifies sustained type I interferon signaling as essential for the development of functional tertiary lymphoid structures in the lungs during inflammation.

32 citationstop 4%

mouseexperimental assay

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