Author

Ruben C. Boot

Delft University of TechnologyORCID 0000-0003-4003-8276Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2

Frequent Co-Authors

Anouk van der NetiD· 2 shared Gijsje Hendrika KoenderinkiD· 2 shared Pouyan Esmailzadeh BoukanyiD· 2 shared Erik H.J. DaneniD· 1 shared I. van Dijk· 1 shared James P. ConboyiD· 1 shared Klara BeslmülleriD· 1 shared Margherita TavassoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

Anouk van der NetORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJul 20, 2026

Septins promote breast cancer cell invasion in 3D collagen gels by influencing actin-based protrusion formation

Anouk van der Net, Klara Beslmüller, Nicole van Vliet…·Gijsje Hendrika Koenderink

This study shows that SEPT7 depletion reduces breast cancer cell invasion in 3D collagen gels by affecting actin-based protrusions and cell shape.

DOI 10.64898/2026.07.17.739166

humanexperimental assay

𝕏 PostBluesky

Cancer BiologybioRxivPreprintMay 12, 2025

Cancer cell deformability impacts the rate of confined migration but not decision making

Anouk van der Net, Ruben C. Boot, I. van Dijk…·Gijsje Hendrika Koenderink

This study shows that cancer cell deformability affects their ability to squeeze through narrow spaces but not their decision-making at channel junctions.

DOI 10.1101/2025.05.12.653524

humanexperimental assay

𝕏 PostBluesky