Gijsje Hendrika Koenderink

This paper demonstrates a minimal one-component abscission machinery for synthetic cells using dynamin A, enabling self-dividing synthetic cells.

This study shows that SEPT7 depletion reduces breast cancer cell invasion in 3D collagen gels by affecting actin-based protrusions and cell shape.

This study shows that arterial shear rates influence blood clot structure, composition, and mechanical properties, with higher shear rates leading to stiffer, platelet-rich clots.

This study quantitatively compares the membrane binding and self-assembly of human septin hexamers and octamers using biophysical methods, revealing distinct structural properties and functional implications.

This paper introduces lipid-conjugated DNA (LiNA) to enable programmable fusion between LUVs and GUVs, demonstrating efficient delivery of lipids and proteins to synthetic cells.

The paper introduces a method to quantify cholesterol incorporation in GUVs using MβCD-CL complexes and fluorescent biosensors, showing up to 40 mol% cholesterol content.

This study identifies the distinct and combined roles of actin and vimentin in determining cell viscoelasticity and compression stiffening using mouse embryonic fibroblasts.

This paper introduces DD-TFM, a data-driven 3D traction force microscopy method that models collagen hydrogels as discrete fiber networks, revealing fiber-level matrix deformations caused by endothelial cells.

This study shows that plectin increases fibroblast stiffness and protects against actin network disruption under compression.

This study shows invasive cancer cells alter collagen network mechanics through volume exclusion, adhesion, and contractility, leading to softening and suppression of stress-stiffening.

This study develops optogenetic and chemical genetic tools to rapidly manipulate vimentin intermediate filaments and examines their immediate effects on cellular structures.

This study investigates how matrix stiffness influences spheroid invasion, collagen remodeling, and stress propagation in the ECM using 3D spheroids and stress sensors.

This study shows that cancer cell deformability affects their ability to squeeze through narrow spaces but not their decision-making at channel junctions.

This study investigates how Staphylococcus aureus forms fibrin-based biofilms in cardiovascular infections, showing coagulase is essential and fibrin strands form within 3 hours in human plasma.

This study uses an agent-based model to show that catch-slip bonds enhance the mechanical properties of polymer networks and aid myosin motors in generating contractile forces.

This study shows anillin directly crosslinks microtubules and actin filaments, promoting bundling and sliding, and suggests its role in regulating microtubule-actin crosstalk during cell division.

This study uses a microvessel-on-a-chip model to compare the effects of short and long ultrasound cycles on vascular permeability and sonoporation induced by microbubbles.

This study investigates how EMT-dependent cell-matrix interactions influence unjamming transitions in cancer spheroid invasion using 3D invasion assays and quantitative image analysis.

The paper develops a high-speed microscopy setup to study GUV formation in cDICE, revealing size-selective crossing at the oil-water interface and the effect of proteins on GUV formation.

This study compares automated tools for quantifying fibrous network structures in images, finding that tools reliably measure relative changes but not absolute values.

This paper optimizes the cDICE method to produce high-quality, defect-free GUVs with efficient encapsulation of complex biochemical systems.