Author
AstraZeneca (United Kingdom)ORCID 0000-0003-4009-282XUnclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Rebecca Andrews, Bin Fu, Christina E. Toomey…·Steven F. Lee
This paper introduces ASA-PD, an imaging method to detect and map α-synuclein oligomers in Parkinson's disease brain tissue, revealing a specific subpopulation of nanoscale oligomers as an early hallmark of the disease.
Dimitra Sokolova, Shari Addington Ghansah, Francesca Puletti…·Soyon Youngae Hong
This study identifies astrocyte-derived MFG-E8 as a key mediator of microglial synapse elimination in Alzheimer's disease mouse models, showing its role in synapse loss and potential as a therapeutic target.
Javier Rueda‐Carrasco, Dimitra Sokolova, Sang‐Eun Lee…·Soyon Youngae Hong
Microglia selectively engulf synapses in Alzheimer-like mouse brains via PtdSer-TREM2 signaling.