Author
UK Dementia Research InstituteORCID 0000-0003-0640-2417Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Gerard Crowley, Minjung Kim, Nathanael O’Neill…·Soyon Youngae Hong
This study shows neuronal hyperactivity triggers C1q deposition on synapses, leading to synapse loss, and identifies immunoglobulins as involved in this process.
Christopher Lee, Farah Tasnim, Xiaozhong Huang…·Florent Ginhoux
This study shows that co-culturing iPSC-derived macrophages with hepatocytes enhances macrophage maturation and hepatocyte function through direct cell-cell contact.
Dimitra Sokolova, Shari Addington Ghansah, Francesca Puletti…·Soyon Youngae Hong
This study identifies astrocyte-derived MFG-E8 as a key mediator of microglial synapse elimination in Alzheimer's disease mouse models, showing its role in synapse loss and potential as a therapeutic target.
Sebastiaan De Schepper, Judy Z. Ge, Gerard Crowley…·Soyon Youngae Hong
This study identifies SPP1 as a key mediator of microglial synaptic engulfment in Alzheimer's disease models, showing its role in neuroimmune interactions.
Javier Rueda‐Carrasco, Dimitra Sokolova, Sang‐Eun Lee…·Soyon Youngae Hong
Microglia selectively engulf synapses in Alzheimer-like mouse brains via PtdSer-TREM2 signaling.