Author

Shuai Yuan

Yale UniversityORCID 0000-0003-4037-3429Unclaimed ORCID profile · follow to get notified of new preprints

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Shuai Yuan2 papers · Chinese Academy of Sciences

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Ivan B. LomakiniD· 1 shared Jonathan Joon-Young ParkiD· 1 shared Lei PengiD· 1 shared Matthew B. DongiD· 1 shared Qi SheniD· 1 shared Shenping WuiD· 1 shared Sidi CheniD· 1 shared Swapnil C. DevarkariD· 1 shared

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2020-2020 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Ivan B. LomakinORCID

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1 paper

Recent·Most cited

Molecular BiologyMolecular CellPeer-reviewedOct 30, 2020

Nonstructural protein 1 of SARS-CoV-2 is a potent pathogenicity factor redirecting host protein synthesis machinery toward viral RNA.

Shuai Yuan, Lei Peng, Jonathan Joon-Young Park…·Yong Xiong

This study identifies Nsp1 as a key pathogenicity factor of SARS-CoV-2 that redirects host translation machinery to viral RNA by inhibiting cellular protein synthesis and altering gene expression programs.

177 citationstop 1%

humanbulk RNA-seq

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