Lei Peng

The paper introduces Brain-DiT, a deep generative model for analyzing task-fMRI data, identifying cognitive regions and subgroups linked to psychiatric conditions like depression and alcohol abuse.

The paper identifies genetic interactions between cancer mutations and immune resistance genes using a CRISPR double knockout screen, revealing potential targets for existing drugs.

This study identifies Nsp1 as a key pathogenicity factor of SARS-CoV-2 that redirects host translation machinery to viral RNA by inhibiting cellular protein synthesis and altering gene expression programs.