GenomicsbioRxivPreprint
Chromosomal rearrangements and instability caused by the LINE-1 retrotransposon
Carlos Mendez‐Dorantes, Xi Zeng, Jennifer A. Karlow…·Cheng-Zhong Zhang
This study uses whole-genome sequencing to show that LINE-1 retrotransposition directly causes chromosomal rearrangements and instability in cancer genomes.