Author

Xi Zeng

Boston Children's HospitalORCID 0000-0002-5355-0773Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Xi Zeng3 papers · Nanjing Tech University

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:variant calling· 2 Approach:experimental assay· 1 Organism:human· 1 Assay:long-read sequencing· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Eunjung Alice LeeiD· 2 shared Kathleen H. BurnsiD· 2 shared Aidan BurniD· 1 shared Alan P. BoyleiD· 1 shared Alexander Eckehart UrbaniD· 1 shared Arnaz Maryam TariqiD· 1 shared Benpeng MiaoiD· 1 shared Boxun ZhaoiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersGenomics

Eunjung Alice LeeORCID

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2 papers

Recent·Most cited

Multi-platform framework for mapping somatic retrotransposition in human tissues

Seunghyun Wang, Mingyun Bae, Jinhao Wang, Boxun Zhao, Khue P. Nguyen, Shayna Mallett, Jessica A. Switzenberg, Steven J. Losh, Corinne E. Sexton, Benpeng Miao, Shihua Dong, Xi Zeng, Ziying Wang, Torrin L. McDonald, Camille Mumm, , Eunjung Alice Lee

The paper develops a framework to detect and trace somatic retrotransposition events in human tissues, identifying rare L1 insertions and improving detection accuracy.

bioRxiv · Oct 7, 2025 · PreprintGenomics

Chromosomal rearrangements and instability caused by the LINE-1 retrotransposon

Carlos Mendez‐Dorantes, Xi Zeng, Jennifer A. Karlow, Phillip Schofield, Serafina Turner, Matthew Joseph Leventhal, Jupiter C. Kalinowski, Jinyu Wang, Sonia Zumalave, Jose M. C. Tubio, Eunjung Alice Lee, Kathleen H. Burns, Cheng-Zhong Zhang

This study uses whole-genome sequencing to show that LINE-1 retrotransposition directly causes chromosomal rearrangements and instability in cancer genomes.

bioRxiv · Dec 14, 2024 · PreprintGenomics