Luis A. Rajman

This study shows that long-term NMN treatment improves healthspan and extends lifespan in female mice but not males, with sex-specific effects on metabolism and microbiome.

The paper shows that DNA double-strand breaks induce epigenomic changes that accelerate the aging clock in mammals.

The paper shows that inducing DNA breaks accelerates aging-related chromatin changes and loss of cell identity in mammals.

This paper demonstrates that epigenetic reprogramming using OSK genes can reverse age-related and injury-induced vision loss in mice by resetting DNA methylation patterns and promoting axon regeneration.