Sheela A. Abraham

The paper compares functional properties of human hematopoietic stem and progenitor cells (HSPCs) from two bone regions, finding similar intrinsic properties but distinct extracellular vesicle effects on quiescence.

This study isolates extracellular vesicles from minimal ascites fluid using strong anion exchange magnetic beads, enhancing proteomic depth and identifying new proteins and SERS signatures in ovarian cancer-derived EVs.

This study shows that SMARCA4 loss in endometrial cancer leads to cell state chaos, not stemness, causing dedifferentiation through epigenomic dysregulation.

This study introduces a new protocol to isolate and enrich extracellular vesicles from human trabecular bone and bone marrow without enzymatic digestion or long-term culture.