Farzaneh Afzali

This study shows that mitochondrial ETF insufficiency promotes cancer growth by reprogramming bioenergetics and signaling pathways in neoplastic cells.

This study isolates extracellular vesicles from minimal ascites fluid using strong anion exchange magnetic beads, enhancing proteomic depth and identifying new proteins and SERS signatures in ovarian cancer-derived EVs.

This study shows that SMARCA4 loss in endometrial cancer leads to cell state chaos, not stemness, causing dedifferentiation through epigenomic dysregulation.

This study shows that both mTOR activation and inhibition increase H3K27me3 through distinct mechanisms, and this epigenetic change correlates with the anti-proliferative effects of mTOR inhibitors.

This study designs a multi-epitope T vaccine targeting TPX2 in HCC using immunoinformatics tools, showing stability, immunogenicity, and potential for TLR4 activation.

This study identifies key circRNAs, RBPs, miRNAs, and mRNAs in breast cancer through systems biology approaches, revealing potential therapeutic targets and regulatory mechanisms.