BioinformaticsJACS AuPeer-reviewed
SynPROTAC: synthesizable PROTACs design through synthesis constrained generative model and reinforcement learning
Mingyuan Xu, Chaoming Huang, Li Pang…·Jinping Lei
SynPROTAC generates novel PROTAC molecules with feasible synthetic routes and favorable properties using a synthesis-constrained generative model and reinforcement learning.
DOI 10.1021/jacsau.6c00732