Alessia Visconti

This study uses 3D diffusion autoencoders to derive latent cardiac MRI phenotypes, finds they share a genetic basis with cardiometabolic traits, and shows predictive power for disease risk.

The paper presents a method to discover new human gut viruses using enriched virome samples and reports over 162,000 novel viral sequences.

This study presents the first large-scale IgA glycomics dataset from twins, identifies shared and specific genetic loci influencing IgA and IgG glycosylation, and shows genetic conservation across ethnicities.

This study shows that gut microbiota-dependent phenylacetic acid (PAA) increases endothelial cell senescence and impairs angiogenesis in aging, with acetate able to reverse these effects.

The paper identifies X-linked genes that escape X-inactivation in twins across tissues, showing variability between individuals and suggesting genetic and environmental influences.

The paper identifies heritable symptoms of SARS-CoV-2 infection using twin studies of self-reported symptoms from the TwinsUK cohort.

This paper identifies novel pleiotropic risk loci for melanoma and nevus density, implicating multiple biological pathways and gene expression under MITF regulation.

YAMP provides a containerised workflow for analysing whole shotgun metagenomic data, ensuring reproducibility and ease of use across UNIX-like systems.

The paper finds that genetic risk for neuropsychiatric diseases is linked to reduced deep grey matter volume in preterm infants, suggesting a mechanism for how early adversity interacts with genetic vulnerability.

PopPAnTe is a Java program for association testing in related samples, handling both family data and genetic similarity-based analyses for quantitative omics data.