Albert Bondt

The paper examines IgG4 antibody repertoire stability over time in health and autoimmune diseases, finding that most clones remain stable despite treatment.

The paper identifies structurally promiscuous IgA1 clones in human serum that exist as both monomers and J-chain-coupled dimers, challenging the view that these forms are clonally distinct.

The paper introduces an LC-MS method to analyze IgG4 repertoires with clonal resolution, revealing high diversity and persistence of IgG4 molecules in serum over time.

This study tracks longitudinal changes in the plasma proteome and complexome of kidney failure patients before and after transplantation, revealing acute phase protein dynamics and macromolecular complex formation during inflammation.

This study presents the first large-scale IgA glycomics dataset from twins, identifies shared and specific genetic loci influencing IgA and IgG glycosylation, and shows genetic conservation across ethnicities.

The paper identifies CD5L as a component of circulatory IgM, showing it forms a complex with J-chain-containing pentamers and affects IgM receptor binding.