Author

Ioannis Spiliotis

University of OxfordORCID 0000-0003-4171-9612Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Assay:electrophysiology· 1

Frequent Co-Authors

Anna L. GloyniD· 2 shared Benoît HastoyiD· 2 shared Martijn van de BuntiD· 2 shared Patrik RorsmaniD· 2 shared Amy Barrett· 1 shared Andrei TarasoviD· 1 shared Andria Theodoulou· 1 shared Ann-Marie T. Richard· 1 shared

Activity by Year

2017-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersGenetics

Anna L. GloynORCID

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2 papers

Recent·Most cited

GeneticsNature GeneticsPeer-reviewedNov 1, 2019

Loss of ZnT8 function protects against diabetes by enhanced insulin secretion

Om Prakash Dwivedi, Mikko Lehtovirta, Benoît Hastoy…·Leif Groop

The paper shows that a loss-of-function variant in ZnT8 improves insulin secretion and protects against type 2 diabetes by enhancing glucose responsiveness and proinsulin conversion.

144 citationstop 1%

humanexperimental assay

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Cell BiologybioRxivPreprintNov 29, 2017

Electrophysiological properties of human β-cell lines EndoC-βH1 and -βH2 conform with human β-cells

Benoît Hastoy, Mahdieh Godazgar, Anne Clark…·Patrik Rorsman

This study examines the electrophysiological and secretory properties of human β-cell lines EndoC-βH1 and -βH2, finding they closely resemble primary human β-cells in insulin secretion and ion channel behavior.

DOI 10.1101/226282

humanelectrophysiology

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