Cynthia Pérez Estrada

This paper reports the 3D genome architecture of a 52,000-year-old woolly mammoth using a novel method, revealing conserved epigenetic features across elephantids.

The paper investigates fibrotic scarring in CNS lesions across species and lesion types, finding pericyte-derived fibrosis as a conserved mechanism.

The paper analyzes synteny patterns across insect genomes, finding that synteny scales with clade age and that some beetle chromosomes maintain gene order over 200 million years.

The paper uses super-resolution imaging and integrative modeling to achieve 10 kb resolution of chromosome folding.

Point-and-click correction of misassemblies on Hi-C heatmaps, paired with the automated 3D-DNA pipeline, gave chromosome-length wombat, opossum and raccoon scaffolds from just short-insert DNA-Seq and in situ Hi-C reads.