Author

Guillaume Heger

École Centrale de NantesORCID 0000-0003-4175-133XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Agnieszka KonopackaiD· 1 shared Alvis BrāzmaiD· 1 shared Andrew B. BenowitziD· 1 shared Aurore SaudemontiD· 1 shared C. Cameron Taylor· 1 shared Carlos Martinez-Fleites· 1 shared Charlotte Mary DeaneiD· 1 shared Danielle L. SchmittiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

Agnieszka KonopackaORCID

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2 papers

Recent·Most cited

BiochemistryACS Chemical BiologyPeer-reviewedNov 2, 2025

Orthogonal IMiD-Degron Pairs Induce Selective Protein Degradation in Cells

Patrick J. Brennan, Rebecca E. Saunders, Mary Spanou…·Stuart J. Conway

The paper designs a selective protein degradation system using bumped IMiD analogs and zinc-finger degrons to target specific proteins without affecting endogenous substrates.

10 citations

protein structureexperimental assay

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Developmental BiologyFrontiers in Cell and Developmental BiologyPeer-reviewedNov 13, 2023

Canonical Wnt and TGF-β/BMP signaling enhance melanocyte regeneration and suppress invasiveness, migration, and proliferation of melanoma cells

Esra Katkat, Yeliz Demirci, Guillaume Heger…·Günes Özhan

The paper compares gene expression in melanocyte regeneration and melanoma to identify signaling pathways that promote regeneration and suppress cancer traits.

23 citations

zebrafishhuman

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