Sebastian Keller

The paper presents 154 new Myxococcota genomes, expands taxonomy, and identifies novel natural products, highlighting their biosynthetic potential for drug discovery.

StructGuy predicts functional effects of genetic variants using a data leakage-free supervised approach, achieving competitive performance against zero-shot methods.

MetaProFi is a Bloom filter-based tool that stores and queries sequence data, enabling efficient and accurate identification of functionally relevant genetic variants by supporting amino acid and translated nucleotide sequences.

This paper introduces a method to identify biologically meaningful structural motifs in protein 3D structures using frequent subgraph mining, validated on known motifs and novel discoveries.