Kirsty Sawicka

This paper introduces a 3D imaging pipeline to detect functionally perfused vasculogenic mimicry in mouse tumor models, providing evidence of its presence and functionality.

Serval is a modular framework for decoding spatial transcriptomics data that introduces Cosine, a method improving transcript recovery and correlation with expression references.

The paper identifies compartment-specific FMRP targets in CA1 pyramidal neurons and shows how FMRP regulates different mRNA functions in cell bodies and dendrites.

ExSeq enables multiplexed RNA mapping at nanoscale resolution by expanding biological specimens for in situ sequencing.

The paper develops a mouse model to identify FMRP mRNA targets in specific neurons, revealing that FMRP binds to a ranked subset of long genes related to Fragile X phenotypes.

This study investigates how a mutation in FMRP's KH2 domain affects FXG association and abundance in different brain regions, revealing circuit-dependent regulation mechanisms.

This study identifies ZFP36 RNA-binding proteins as regulators of T-cell activation and anti-viral immunity, showing they restrain T-cell expansion and effector functions.