Luke L. Cai

This study shows PKMYT1 inhibition causes DNA damage and enhances anti-PD-1 therapy in CCNE1-amplified gastroesophageal adenocarcinoma.

micronuclAI automates micronuclei quantification to assess chromosomal instability, achieving near-human performance on cancer cell line images.

This study identifies GCL inhibition as a strategy to induce ferroptosis in cancer cells, introducing novel inhibitors with potent cellular activity.