Dewison Ricardo Ambrizi

This study evaluates a multi-target small-molecule cocktail, GUSTC, to reduce repressive heterochromatin marks in bovine fibroblasts, enhancing reprogramming potential without improving embryo development.

This study examines how varying oxygen concentrations during in vitro maturation and fertilization affect bovine embryo production, metabolism, and epigenetic marks.

This study validates a single oocyte biopsy method in bovine by comparing it to whole oocytes, showing high correlation in gene expression despite minor differences.

This paper predicts oocyte competence in bovine using RNA-seq and WGBS from biopsies, cumulus cells, granulosa cells, and polar bodies, identifying transcriptional and epigenetic differences between cleaved but arrested and blastocyst-stage embryos.

This study inhibits EHMT1/2 with UNC0638 in bovine cells during reprogramming, reducing H3K9me2 and other marks but not improving preimplantation development.