Felipe Perecin

The paper shows that placental phenotypes in mammals can be predicted from miRNA repertoires with high accuracy, revealing constrained genetic pathways for convergent evolution.

This study validates a single oocyte biopsy method in bovine by comparing it to whole oocytes, showing high correlation in gene expression despite minor differences.

This paper predicts oocyte competence in bovine using RNA-seq and WGBS from biopsies, cumulus cells, granulosa cells, and polar bodies, identifying transcriptional and epigenetic differences between cleaved but arrested and blastocyst-stage embryos.

The paper investigates the effects of beta-hydroxybutyrate on histone lysine beta-hydroxybutyrylation and transcriptome changes in bovine fibroblasts and cumulus-oocyte complexes, showing altered gene expression but no impact on oocyte meiotic competence.

This study inhibits EHMT1/2 with UNC0638 in bovine cells during reprogramming, reducing H3K9me2 and other marks but not improving preimplantation development.