Ricardo Perecin Nociti

Epigenetic Remodeling Increases Plasticity of Bovine Fibroblasts Without Improving Embryo and Stem Cell Development

This study evaluates a multi-target small-molecule cocktail, GUSTC, to reduce repressive heterochromatin marks in bovine fibroblasts, enhancing reprogramming potential without improving embryo development.

Biosensor capability of the endometrium is mediated in part, by altered miRNA cargo from conceptus-derived extracellular vesicles.

The paper investigates how endometrial biosensor capability is influenced by miRNA cargo in conceptus-derived extracellular vesicles during peri-implantation, showing differential miRNA effects on endometrial gene expression.

Artificial environment impact: O2 concentration changes between IVM and IVF alter embryo production, metabolism, and epigenetic marks

This study examines how varying oxygen concentrations during in vitro maturation and fertilization affect bovine embryo production, metabolism, and epigenetic marks.

An exploratory data analysis from ovine and bovine RNA-seq identifies pathways and key genes related to cervical dilatation

The paper analyzes RNA-seq data from cattle and sheep to identify genes and pathways associated with cervical dilatation during reproductive cycles.

Assessment of Total Oocyte Transcripts Representation through Single Ooplasm Biopsy in Bovine with High Reliability

This study validates a single oocyte biopsy method in bovine by comparing it to whole oocytes, showing high correlation in gene expression despite minor differences.

Retrospective model utilizing biopsies, granulosa cells, and polar body to predict oocyte competence in bovine

This paper predicts oocyte competence in bovine using RNA-seq and WGBS from biopsies, cumulus cells, granulosa cells, and polar bodies, identifying transcriptional and epigenetic differences between cleaved but arrested and blastocyst-stage embryos.

Haploid androgenetic development in bovines reveals imbalanced WNT signaling and impaired cell fate differentiation.

This study identifies imbalanced WNT signaling and altered pluripotency markers in bovine haploid androgenetic embryos, showing that WNT pathway modulation can improve blastocyst formation.

The central role of pyruvate metabolism on the epigenetic and molecular maturation of bovine cumulus-oocytes complexes.

This study examines how pyruvate metabolism affects histone acetylation and gene expression in bovine oocytes during in vitro maturation.

Characterization of Histone Lysine β-hydroxybutyrylation in bovine tissues, cells, and cumulus-oocyte complexes

The paper investigates the effects of beta-hydroxybutyrate on histone lysine beta-hydroxybutyrylation and transcriptome changes in bovine fibroblasts and cumulus-oocyte complexes, showing altered gene expression but no impact on oocyte meiotic competence.

CeTF: an R package to Coexpression forTranscription Factors using Regulatory ImpactFactors (RIF) and Partial Correlation andInformation (PCIT) analysis

CeTF identifies transcription factors regulating gene networks using PCIT and RIF analysis on gene expression data from various platforms.